When traveling on I-95 or I-20, the Holiday Inn Express is the preferred overnight choice of many travelers. Just minutes away from the finest restaurants, attractions and shopping in the area, the Holiday Inn Express is conveniently located at the intersection of I-95 and I-20. Our central location brings travelers to our city year after year. We are located midway between Miami and New York as well as centrally located to the beautiful beaches of North and South Carolina. No matter what brings you to Florence, You will feel right at home at the Holiday Inn Express. Whether it?s to attend a business meeting, visit old friends, or even if you?re just passing through, from the minute you walk through our door, you will experience the finest in accommodations, amenities and service that Florence has to offer.The Holiday Inn Express is designed to meet the needs of our corporate, family, leisure and group travelers. Packed with amenities such as Micro-fridges and In-room coffee, our combination of rooms with two queen or one king size beds, as well as Jacuzzi and accessible rooms enable us to meet all your needs. In addition, our 625 square foot classroom is great for small meetings, presentations, receptions or any other small gatherings.Old Southern charm meets the hustle and bustle of modern life at the award-winning Holiday Inn Express, Florence. Come and share an unforgettable experience with us.